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Comparison of genomes by synteny block analysis
Pavel, Tomáš ; Škutková, Helena (referee) ; Maděránková, Denisa (advisor)
The theoretical part of this bachelor thesis is aimed at basics of genetics. Term of gene and mutation are introduced in this section. There are gene and chromosome mutations mentioned and described. Following section is devoted to comparative genomics and especially to synteny. There is described what the synteny actually is and how the synteny arises. The end of the theoretical part of this thesis is about the evolution and there are described ways of sorting permutation vectors. The practical part of this bachelor thesis includes description of developed software. Output of this software is a dot-plot which shows detected synteny blocks. Indexes of these blocks are listed in GUI. The second important output is number of permutation steps. This number determines evolutionary distance between two analysed DNA sequences. The very last section is aimed at analyse of synthetic and real DNA sequences.
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Examining the impact of reforms on economic growth: The case of transition economies
Zhupaj, Lorena ; Horváth, Roman (advisor) ; Benáček, Vladimír (referee)
This paper aims to investigate the impact of reforms on economic growth in a sample of transition economies of Central Eastern Europe, South Eastern Europe and Commonwealth of Independent States from 1989 until 2010. We employ a panel data methodology and run a Haussman test to distinguish between a fixed effect and a random effect model. In addition, we take into account the role of reform reversals and examine their contribution in the growth dynamics. Reform downgrades are very common since in some cases progress in reforms has been stalled or even reversed due to political instability, wars, economic crises, etc. We model the reforms downgrades following the previous work of Merlevede (2003) using a different methodology and extending our period of estimation. Furthermore, the relationship between other explanatory variables (i.e. initial conditions, fiscal balance) and growth is further explored in the empirical estimation. JEL Classification O57, P21 Keywords transition economies, reforms, reversal Author's e-mail lorena_zh@hotmail.com Supervisor's e-mail roman.horvath@gmail.com
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Examining the impact of reforms on economic growth: The case of transition economies
Zhupaj, Lorena ; Horváth, Roman (advisor) ; Benáček, Vladimír (referee)
This paper aims to investigate the impact of reforms on economic growth in a sample of transition economies of Central Eastern Europe, South Eastern Europe and Commonwealth of Independent States from 1989 until 2010. We employ a panel data methodology and run a Haussman test to distinguish between a fixed effect and a random effect model. In addition, we take into account the role of reform reversals and examine their contribution in the growth dynamics. Reform downgrades are very common since in some cases progress in reforms has been stalled or even reversed due to political instability, wars, economic crises, etc. We model the reforms downgrades following the previous work of Merlevede (2003) using a different methodology and extending our period of estimation. Furthermore, the relationship between other explanatory variables (i.e. initial conditions, fiscal balance) and growth is further explored in the empirical estimation. JEL Classification O57, P21 Keywords transition economies, reforms, reversal Author's e-mail lorena_zh@hotmail.com Supervisor's e-mail roman.horvath@gmail.com
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Comparison of genomes by synteny block analysis
Pavel, Tomáš ; Škutková, Helena (referee) ; Maděránková, Denisa (advisor)
The theoretical part of this bachelor thesis is aimed at basics of genetics. Term of gene and mutation are introduced in this section. There are gene and chromosome mutations mentioned and described. Following section is devoted to comparative genomics and especially to synteny. There is described what the synteny actually is and how the synteny arises. The end of the theoretical part of this thesis is about the evolution and there are described ways of sorting permutation vectors. The practical part of this bachelor thesis includes description of developed software. Output of this software is a dot-plot which shows detected synteny blocks. Indexes of these blocks are listed in GUI. The second important output is number of permutation steps. This number determines evolutionary distance between two analysed DNA sequences. The very last section is aimed at analyse of synthetic and real DNA sequences.
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